Description

3-[6-Oxo-2-Propyl-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated heterocyclic scaffold with a propanoic acid side chain for further functionalization. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for targeted therapies.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• API Development: Serves as a precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Potential use as a tool compound or probe in biochemical assays and target validation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for advanced organic synthesis and heterocyclic chemistry projects.

Basic Information

Product Name	3-[6-Oxo-2-Propyl-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid
CAS No.	1018165-97-3
Molecular Formula	C13H14F3N3O3
Molecular Weight	317.26 g/mol
Synonyms	7-(2-Carboxyethyl)-2-propyl-4-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridin-6(7H)-one; 3-(6-Oxo-2-propyl-4-(trifluoromethyl)-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid; 2-Propyl-4-(trifluoromethyl)-7-(2-carboxyethyl)-2H-pyrazolo[3,4-b]pyridin-6(7H)-one; 1018165-97-3; Propanoic acid, 3-[6-oxo-2-propyl-4-(trifluoromethyl)-2,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]-; TRIFLUOROMETHYL PYRAZOLOPYRIDINE PROPANOIC ACID DERIVATIVE
EINECS	Contact for details

Quality Control

Our 3-[6-Oxo-2-Propyl-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.