Description

3-[4-(Difluoromethyl)-2-Ethyl-3-Methyl-6-Oxo-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the fields of oncology and metabolic disease. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers requiring reliable, high-quality building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Drug Discovery Research: Used in medicinal chemistry for the design and optimization of new drug candidates, particularly kinase inhibitors.
• Biochemical Research: Serves as a reference standard or a probe compound in biochemical and pharmacological assays.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to construct complex molecular architectures for specialized applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Product Name	3-[4-(Difluoromethyl)-2-Ethyl-3-Methyl-6-Oxo-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid
CAS No.	1018165-50-8
Molecular Formula	C15H17F2N3O3
Molecular Weight	325.31 g/mol
Synonyms	7H-Pyrazolo[3,4-b]pyridine-7-propanoic acid, 4-(difluoromethyl)-2-ethyl-2,6-dihydro-3-methyl-6-oxo-; 3-[4-(Difluoromethyl)-2-ethyl-3-methyl-6-oxo-1,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]propanoic acid; 1018165-50-8; Difluoromethyl pyrazolopyridine propanoic acid derivative; Pyrazolopyridine carboxylic acid intermediate
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Difluoromethyl)-2-Ethyl-3-Methyl-6-Oxo-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid adheres to stringent quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all critical quality attributes. We support development and commercial projects with material produced under quality guidelines suitable for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound is stable under these conditions but should be kept away from strong acids and oxidizing agents. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.