Description

6-Chloro-4-(difluoromethyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine is a high-purity, advanced pharmaceutical intermediate and organic building block. This compound is valued for its unique heterocyclic structure, which serves as a critical scaffold in modern medicinal chemistry and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its difluoromethyl and pyrazolopyridine motifs.
• Chemical Biology: Serves as a versatile probe or ligand in the study of protein-ligand interactions and enzyme inhibition.
• Material Science: Potential precursor for the synthesis of specialty chemicals and functional materials with specific electronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations engaged in custom synthesis and process scale-up for client projects.

Basic Information

Product Name	6-Chloro-4-(difluoromethyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine
CAS No.	1018165-42-8
Molecular Formula	C9H6ClF2N3
Molecular Weight	229.61 g/mol
Synonyms	6-Chloro-4-(difluoromethyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine; 2H-Pyrazolo[3,4-b]pyridine, 6-chloro-4-(difluoromethyl)-2-methyl-; 1018165-42-8; 6-Chloro-4-difluoromethyl-2-methyl-2H-pyrazolo[3,4-b]pyridine; 4-(Difluoromethyl)-6-chloro-2-methyl-2H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(difluoromethyl)-2-methyl-2H-pyrazolo[3,4-b]pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.