Description

3-[4-(Difluoromethyl)-2-Methyl-6-Oxo-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly for synthesizing novel active pharmaceutical ingredients (APIs). It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new therapeutic agents, especially in oncology and metabolic disease research.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs in drug discovery.
• API Synthesis: Serves as a crucial precursor in the multi-step synthesis of complex final active pharmaceutical ingredients.
• Biochemical Research: Potential tool compound for studying enzyme inhibition or modulating specific biological targets due to its unique pyrazolopyridine core.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects under cGMP conditions.
• Academic Research: Utilized in university and institutional labs for exploratory synthetic chemistry and novel heterocycle development.

Basic Information

Product Name	3-[4-(Difluoromethyl)-2-Methyl-6-Oxo-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid
CAS No.	1018165-34-8
Molecular Formula	C12H11F2N3O3
Molecular Weight	283.23 g/mol
Synonyms	7-(2-Carboxyethyl)-4-(difluoromethyl)-2-methyl-2H-pyrazolo[3,4-b]pyridin-6(7H)-one; 3-[4-(Difluoromethyl)-2-methyl-6-oxo-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-7-yl]propanoic acid; 1018165-34-8; Propanoic acid, 3-[4-(difluoromethyl)-2-methyl-6-oxo-2,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]-; Pyrazolopyridine propanoic acid derivative; DFMPP intermediate
EINECS	Contact for details

Quality Control

Our production of 3-[4-(Difluoromethyl)-2-Methyl-6-Oxo-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the exacting standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided for every shipment, and custom synthesis can be performed under controlled conditions to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is light-sensitive and should be handled accordingly. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.