Description

6-Chloro-2,3-Dimethyl-4-(Trifluoromethyl)-2H-Pyrazolo[3,4-B]Pyridine is a high-value, multi-functional heterocyclic building block designed for advanced chemical synthesis. Its core value lies in its unique molecular architecture, which combines a halogenated pyridine core with a pyrazole ring and a trifluoromethyl group, offering significant potential for modulating the physicochemical properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a critical intermediate in the development of novel active ingredients.

Application

This specialized pyrazolopyridine derivative is a versatile scaffold with applications across several high-tech sectors.

• Pharmaceutical Intermediate: A key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors, anti-inflammatory agents, and central nervous system (CNS) active compounds.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Material Science Precursor: Serves as an advanced intermediate for creating functional organic materials, such as ligands for catalysts or components in organic electronic devices.
• Chemical Biology Probe: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical raw material for CDMOs (Contract Development and Manufacturing Organizations) engaged in producing complex molecules for client R&D and scale-up projects.

Basic Information

Product Name	6-Chloro-2,3-Dimethyl-4-(Trifluoromethyl)-2H-Pyrazolo[3,4-B]Pyridine
CAS No.	1018165-26-8
Molecular Formula	C10H7ClF3N3
Molecular Weight	261.63 g/mol
Synonyms	6-Chloro-2,3-dimethyl-4-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridine; 2H-Pyrazolo[3,4-b]pyridine, 6-chloro-2,3-dimethyl-4-(trifluoromethyl)-; 1018165-26-8; 6-Chloro-2,3-dimethyl-4-trifluoromethyl-2H-pyrazolo[3,4-b]pyridine; 6-Chloro-2,3-dimethyl-4-(trifluoromethyl)pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our production of 6-Chloro-2,3-Dimethyl-4-(Trifluoromethyl)-2H-Pyrazolo[3,4-B]Pyridine adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. All material is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with global regulatory frameworks, including REACH and ICH guidelines, for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.