Description

6-Chloro-4-(difluoromethyl)-2-ethyl-3-methyl-2H-pyrazolo[3,4-b]pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique pyrazolopyridine core structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A critical precursor in the research and synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Serves as a key scaffold for developing new generation pesticides and herbicides with enhanced efficacy.
• Chemical Biology & Proteomics: Used as a molecular probe or a tagged ligand in biochemical assays and target identification studies.
• Material Science Research: Potential building block for creating organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, heteroaromatic structure.
• Contract Research & Development (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in heterocyclic and fluorine chemistry.

Basic Information

Product Name	6-Chloro-4-(difluoromethyl)-2-ethyl-3-methyl-2H-pyrazolo[3,4-b]pyridine
CAS No.	1018165-01-9
Molecular Formula	C12H12ClF2N3
Molecular Weight	271.69 g/mol
Synonyms	6-Chloro-4-(difluoromethyl)-2-ethyl-3-methyl-2H-pyrazolo[3,4-b]pyridine; 2H-Pyrazolo[3,4-b]pyridine, 6-chloro-4-(difluoromethyl)-2-ethyl-3-methyl-; 1018165-01-9; 6-Chloro-4-difluoromethyl-2-ethyl-3-methyl-2H-pyrazolo[3,4-b]pyridine; 2-Ethyl-3-methyl-6-chloro-4-(difluoromethyl)-2H-pyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(difluoromethyl)-2-ethyl-3-methyl-2H-pyrazolo[3,4-b]pyridine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and development use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.