Description

3-Cyclopropyl-6-Isopropyl-1-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel drug candidates, especially in oncology and antiviral research.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing complex pyrazolopyridine scaffolds with potential biological activity.
• Research & Development (R&D): Essential for academic and industrial R&D labs exploring new heterocyclic compounds and their pharmacological properties.
• Process Chemistry: Employed in scale-up and optimization studies for the commercial production of target APIs.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	3-Cyclopropyl-6-Isopropyl-1-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1018164-86-7
Molecular Formula	C21H21N3O2
Molecular Weight	347.41 g/mol
Synonyms	3-Cyclopropyl-6-(propan-2-yl)-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-Phenyl-3-cyclopropyl-6-isopropyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3-cyclopropyl-6-(1-methylethyl)-1-phenyl-; 1018164-86-7; 3-Cyclopropyl-6-isopropyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our production of 3-Cyclopropyl-6-Isopropyl-1-Phenyl-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting full specifications are provided with each shipment. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.