Description

2-Butyl-4-(Difluoromethyl)-3-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-purity, advanced pharmaceutical intermediate of significant commercial interest. This compound is valued for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting kinase inhibition.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization programs.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex pyrazolopyridine-based molecular architectures.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects under cGMP conditions.
• Agrochemical Research: Potential application as an intermediate in the development of novel crop protection agents with specific biological activity.

Basic Information

Product Name	2-Butyl-4-(Difluoromethyl)-3-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018163-84-2
Molecular Formula	C₁₃H₁₅F₂N₃O
Molecular Weight	267.27 g/mol
Synonyms	2-Butyl-4-(difluoromethyl)-3-methyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 2-Butyl-4-(difluoromethyl)-3-methyl-2H,6H,7H-pyrazolo[3,4-b]pyridin-6-one; 1018163-84-2; 2H,6H,7H-Pyrazolo[3,4-b]pyridin-6-one, 2-butyl-4-(difluoromethyl)-3-methyl-; Pyrazolo[3,4-b]pyridin-6-one derivative; CAS 1018163-84-2
EINECS	Contact for details

Quality Control

Our 2-Butyl-4-(Difluoromethyl)-3-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with complete analytical data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.