Description

2-Cyclopentyl-4-(Difluoromethyl)-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, heterocyclic organic compound serving as a critical building block in advanced pharmaceutical research and development. Its unique fused pyrazolopyridine core, functionalized with cyclopentyl and difluoromethyl groups, makes it a versatile intermediate for constructing novel bioactive molecules. This compound is primarily sought by medicinal chemists and process development scientists in the pharmaceutical and biotechnology sectors for the synthesis of targeted therapeutics.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting a range of diseases.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its modifiable scaffold.
• Kinase Inhibitor Development: The pyrazolopyridine structure is a privileged scaffold in the design of potent and selective kinase inhibitors for oncology and inflammatory diseases.
• Process Chemistry & Scale-Up: Serves as a defined intermediate in the development of robust, scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Chemical Biology Probes: Utilized in the creation of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	2-Cyclopentyl-4-(Difluoromethyl)-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018163-80-8
Molecular Formula	C13H13F2N3O
Molecular Weight	265.26 g/mol
Synonyms	2-Cyclopentyl-4-(difluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 6H-Pyrazolo[3,4-b]pyridin-6-one, 2-cyclopentyl-4-(difluoromethyl)-2,7-dihydro-; 1018163-80-8; 2-Cyclopentyl-4-difluoromethyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 2-Cyclopentyl-4-(difluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridine-6-one; 2-Cyclopentyl-4-(difluoromethyl)-6H-pyrazolo[3,4-b]pyridin-6-one; 2-Cyclopentyl-4-(difluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridine-6-one
EINECS	Contact for details

Quality Control

Our 2-Cyclopentyl-4-(Difluoromethyl)-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed specifications to ensure traceability and compliance with your research or development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.