Description

3-(4-Methoxyphenyl)-6-Methylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders or inflammatory pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening (HTS) campaigns to identify new biological activity.
• API Development: Used in the research and process optimization stages for developing new Active Pharmaceutical Ingredients (APIs) with an isoxazolopyridine core.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs supporting outsourced drug discovery and development projects for global clients.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry, reaction mechanisms, and structure-activity relationships (SAR).

Basic Information

Item	Details
Product Name	3-(4-Methoxyphenyl)-6-Methylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1018143-33-3
Molecular Formula	C16H12N2O4
Molecular Weight	296.28 g/mol
Synonyms	6-Methyl-3-(4-methoxyphenyl)isoxazolo[5,4-b]pyridine-4-carboxylic acid; 3-(4-Methoxyphenyl)-6-methyl[1,2]oxazolo[5,4-b]pyridine-4-carboxylic acid; 1018143-33-3; Isoxazolo[5,4-b]pyridine-4-carboxylic acid, 3-(4-methoxyphenyl)-6-methyl-
EINECS	Contact for details

Quality Control

Our production of 3-(4-Methoxyphenyl)-6-Methylisoxazolo[5,4-B]Pyridine-4-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or cGMP starting material requirements, as applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.