Description

6-Chloro-4-(difluoromethyl)-2-isopropyl-2H-pyrazolo[3,4-b]pyridine is a high-purity, advanced pharmaceutical intermediate and heterocyclic building block. This compound is valued for its unique pyrazolopyridine core, which is integral to the synthesis of novel bioactive molecules. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Serves as a precursor for the synthesis of specialty chemicals and functional materials, including ligands for catalysis.
• Academic & Contract Research: Employed in medicinal chemistry programs and process development for scale-up synthesis in laboratory and pilot plant settings.

Basic Information

Product Name	6-Chloro-4-(difluoromethyl)-2-isopropyl-2H-pyrazolo[3,4-b]pyridine
CAS No.	1018127-78-0
Molecular Formula	C11H10ClF2N3
Molecular Weight	257.67 g/mol
Synonyms	6-Chloro-4-(difluoromethyl)-2-(propan-2-yl)-2H-pyrazolo[3,4-b]pyridine; 2H-Pyrazolo[3,4-b]pyridine, 6-chloro-4-(difluoromethyl)-2-(1-methylethyl)-; 6-Chloro-4-difluoromethyl-2-isopropyl-2H-pyrazolo[3,4-b]pyridine; 1018127-78-0; 6-Chloro-4-(difluoromethyl)-2-isopropyl-2H-pyrazolo[3,4-b]pyridine; 6-Chloro-4-(difluoromethyl)-2-isopropylpyrazolo[3,4-b]pyridine
EINECS	Contact for details

Quality Control

Our 6-Chloro-4-(difluoromethyl)-2-isopropyl-2H-pyrazolo[3,4-b]pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.