Description

2-(2,2-Difluoroethyl)-3-Methyl-4-(Trifluoromethyl)-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, fluorinated heterocyclic compound, CAS NO 1018127-62-2, serving as a critical building block in modern pharmaceutical discovery. Its complex structure, featuring multiple fluorine atoms, is engineered to enhance metabolic stability, bioavailability, and binding affinity in target molecules. This advanced intermediate is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in oncology, CNS disorders, and anti-inflammatory therapies.
• Agrochemical Research: Used in the synthesis of novel pesticides and herbicides, where the fluorinated pyrazolopyridine core can contribute to improved efficacy and environmental profile.
• Chemical Biology Probe: Serves as a scaffold for developing tool compounds to study biological pathways and protein functions in academic and industrial research settings.
• Material Science Research: Potential building block for specialty polymers or organic electronic materials due to its unique fluorinated aromatic system.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical and agrochemical companies with custom synthesis and process development.

Basic Information

Product Name	2-(2,2-Difluoroethyl)-3-Methyl-4-(Trifluoromethyl)-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018127-62-2
Molecular Formula	C11H8F5N3O
Molecular Weight	293.20 g/mol
Synonyms	2,7-Dihydro-2-(2,2-difluoroethyl)-3-methyl-4-(trifluoromethyl)-6H-pyrazolo[3,4-b]pyridin-6-one; 6H-Pyrazolo[3,4-b]pyridin-6-one, 2,7-dihydro-2-(2,2-difluoroethyl)-3-methyl-4-(trifluoromethyl)-; 1018127-62-2; AKOS040759184; FT-0777689; 2-(2,2-Difluoroethyl)-3-methyl-4-(trifluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; SCHEMBL23346877; 4-(Trifluoromethyl)-2-(2,2-difluoroethyl)-3-methyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
EINECS	Contact for details

Quality Control

Our production of 2-(2,2-Difluoroethyl)-3-Methyl-4-(Trifluoromethyl)-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements or regulatory standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere if necessary to prevent moisture uptake and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.