Description

3-Cyclopropyl-6-Methyl-1-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the pyrazolopyridine class of heterocyclic compounds. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought after by research institutions, contract development and manufacturing organizations (CDMOs), and pharmaceutical companies engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and synthesis of potential new chemical entities (NCEs) for drug discovery programs.
• API Synthesis: Used in the development and scale-up of active pharmaceutical ingredients, especially for candidates with pyrazolopyridine core structures.
• Medicinal Chemistry Research: A valuable scaffold for structure-activity relationship (SAR) studies and lead optimization in academic and industrial R&D labs.
• Contract Manufacturing: Supplied to CDMOs for the production of clinical trial materials and commercial API batches under cGMP standards.
• Biochemical Tool Compound: Potential use in developing biochemical probes for studying enzyme inhibition or receptor modulation.
• Agrochemical Research: May find application as an intermediate in the discovery of new agrochemicals, such as herbicides or fungicides.

Basic Information

Product Name	3-Cyclopropyl-6-Methyl-1-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1018127-41-7
Molecular Formula	C₁₇H₁₅N₃O₂
Molecular Weight	293.32 g/mol
Synonyms	3-Cyclopropyl-6-methyl-1-phenyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3-cyclopropyl-6-methyl-1-phenyl-; 1018127-41-7; 3-Cyclopropyl-6-methyl-1-phenylpyrazolo[3,4-b]pyridine-4-carboxylic acid; 3-Cyclopropyl-1-phenyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-6-Methyl-1-Phenyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.