Description

1-(2-Fluorophenyl)-6-Isopropyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it serves as a critical building block in modern medicinal chemistry, enabling the development of targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in drug discovery programs, particularly for oncology, anti-inflammatory, and central nervous system (CNS) applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting specific biological pathways.
• Kinase Inhibitor Development: Used in research and production of potential kinase inhibitors due to its pyrazolopyridine core structure.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• API Synthesis: Incorporated into the final chemical structure of active pharmaceutical ingredients under development.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Biochemical Research: Utilized as a tool compound for in vitro biological screening and assay development.

Basic Information

Product Name	1-(2-Fluorophenyl)-6-Isopropyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1018127-29-1
Molecular Formula	C₁₇H₁₄FN₃O₂
Molecular Weight	311.31 g/mol
Synonyms	1-(2-Fluorophenyl)-6-(propan-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 6-Isopropyl-1-(2-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 1-(2-fluorophenyl)-6-(1-methylethyl)-; CAS 1018127-29-1; Fluorophenyl Isopropyl Pyrazolopyridine Carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)-6-Isopropyl-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure compliance with research and development grade standards. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.