Description

3-[2-Cyclopentyl-6-Oxo-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development for new chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) research.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and pharmacokinetic properties of new molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
• Reference Standard: Can be supplied as a high-purity analytical standard for method development and quality control in API production.

Basic Information

Product Name	3-[2-Cyclopentyl-6-Oxo-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid
CAS No.	1018127-13-3
Molecular Formula	C15H16F3N3O3
Molecular Weight	343.30 g/mol
Synonyms	7H-Pyrazolo[3,4-b]pyridine-7-propanoic acid, 2-cyclopentyl-2,6-dihydro-6-oxo-4-(trifluoromethyl)-; 3-(2-Cyclopentyl-6-oxo-4-(trifluoromethyl)-6,7-dihydro-2H-pyrazolo[3,4-b]pyridin-7-yl)propanoic acid; 1018127-13-3; UNII-9V6T7QY6IJ; 9V6T7QY6IJ; AKOS025147324; ZINC000103074511
EINECS	Contact for details

Quality Control

Our 3-[2-Cyclopentyl-6-Oxo-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, MS), to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.