Description

3-[2-Ethyl-6-Oxo-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex pyrazolopyridine core structure. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug molecules, especially those targeting specific enzyme pathways.
• Drug Discovery Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization due to its unique heterocyclic framework.
• API Development: Employed in the development and scale-up processes for new active pharmaceutical ingredients, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Biochemical Research: Acts as a tool compound or a reference standard in biochemical assays and pharmacological studies.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CRMOs) for bespoke chemical synthesis projects for clients.

Basic Information

Product Name	3-[2-Ethyl-6-Oxo-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid
CAS No.	1018126-93-6
Molecular Formula	C₁₂H₁₀F₃N₃O₃
Molecular Weight	301.22 g/mol
Synonyms	3-[2-Ethyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]propanoic acid; 2-Ethyl-7-(2-carboxyethyl)-4-(trifluoromethyl)-2H-pyrazolo[3,4-b]pyridin-6(7H)-one; 1018126-93-6; Propanoic acid, 3-[2-ethyl-6-oxo-4-(trifluoromethyl)-2,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl]-; 3-(2-Ethyl-6-oxo-4-trifluoromethyl-2,6-dihydro-7H-pyrazolo[3,4-b]pyridin-7-yl)propionic acid
EINECS	Contact for details

Quality Control

Our production of 3-[2-Ethyl-6-Oxo-4-(Trifluoromethyl)-2,6-Dihydro-7H-Pyrazolo[3,4-B]Pyridin-7-Yl]Propanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and development. All materials are characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong acids, organic solvents, fluorides, and strong alkalis.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.