Description

4-(Difluoromethyl)-2-Ethyl-3-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, heterocyclic organic compound with a CAS registry number of 1018126-34-5. This specialized chemical serves as a critical advanced pharmaceutical intermediate and a versatile building block in modern synthetic chemistry. It is primarily required by R&D and production teams in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates, particularly in kinase inhibitor and other small-molecule therapeutic programs.
• Agrochemical Synthesis: Used in the synthesis of novel pesticides and herbicides, leveraging its unique difluoromethyl-substituted heterocyclic structure for enhanced biological activity.
• Chemical Research & Development: Serves as a versatile scaffold for medicinal chemistry, enabling structure-activity relationship (SAR) studies and the exploration of new chemical entities.
• Material Science: Potential building block for the synthesis of specialized organic electronic materials or ligands for catalytic systems.
• Contract Manufacturing (CMO/CDMO): Supplied to custom synthesis organizations for scale-up and production under cGMP or other stringent quality frameworks for client projects.

Basic Information

Product Name	4-(Difluoromethyl)-2-Ethyl-3-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018126-34-5
Molecular Formula	C₁₁H₁₃F₂N₃O
Molecular Weight	241.24 g/mol
Synonyms	4-(Difluoromethyl)-2-ethyl-3-methyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 2-Ethyl-3-methyl-4-(difluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 1018126-34-5; Pyrazolopyridinone derivative; Difluoromethyl pyrazolopyridinone
EINECS	Contact for details

Quality Control

Every batch of 4-(Difluoromethyl)-2-Ethyl-3-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is manufactured and tested under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for demanding R&D and scale-up applications. Comprehensive Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.