Description

4-(Difluoromethyl)-2-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, heterocyclic organic compound featuring a fused pyrazolo-pyridinone core, distinguished by a difluoromethyl substituent. This structural motif makes it a critical advanced pharmaceutical intermediate (API) and a versatile scaffold in medicinal chemistry for drug discovery programs. It is primarily sought after by pharmaceutical R&D and fine chemical synthesis teams focused on developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery.
• Biochemical Tool Compound: Employed in biological assays and as a probe to study specific enzyme interactions and cellular pathways.
• Organic Synthesis: Acts as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for high-throughput screening.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the life sciences industry.

Basic Information

Product Name	4-(Difluoromethyl)-2-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018126-22-1
Molecular Formula	C9H7F2N3O
Molecular Weight	211.17 g/mol
Synonyms	4-(Difluoromethyl)-2-methyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 2-Methyl-4-(difluoromethyl)-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one; 1018126-22-1; 4-(Difluoromethyl)-2-methyl-6H-pyrazolo[3,4-b]pyridin-6-one; Pyrazolo[3,4-b]pyridin-6-one, 4-(difluoromethyl)-2-methyl-2,7-dihydro-; 4-Difluoromethyl-2-methyl-2,7-dihydro-6H-pyrazolo[3,4-b]pyridin-6-one
EINECS	Contact for details

Quality Control

Our production of 4-(Difluoromethyl)-2-Methyl-2,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.