Description

2-[3-Cyclopropyl-6-Ethyl-4-(Trifluoromethyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters as a key building block in medicinal chemistry, enabling the development of targeted therapeutics with enhanced biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers focused on creating new drug candidates, particularly in areas like oncology and inflammation.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• API Development: Serves as a key scaffold for constructing complex molecules with potential kinase inhibitory or other targeted activities.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.
• Biochemical Research: Employed as a tool compound in biochemical assays to study specific biological pathways and protein interactions.

Basic Information

Product Name	2-[3-Cyclopropyl-6-Ethyl-4-(Trifluoromethyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid
CAS No.	1018125-49-9
Molecular Formula	C₁₄H₁₄F₃N₃O₂
Molecular Weight	313.28 g/mol
Synonyms	2-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)acetic acid; 1H-Pyrazolo[3,4-b]pyridine-1-acetic acid, 3-cyclopropyl-6-ethyl-4-(trifluoromethyl)-; 1018125-49-9; 2-(3-Cyclopropyl-6-ethyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-1-yl)ethanoic acid; Cyclopropyl-ethyl-trifluoromethyl-pyrazolopyridine acetic acid derivative
EINECS	Contact for details

Quality Control

Our 2-[3-Cyclopropyl-6-Ethyl-4-(Trifluoromethyl)Pyrazolo[3,4-B]Pyridin-1-Yl]Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.