Description

3-Cyclopropyl-6-Ethyl-1-(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular scaffolds. It is primarily needed by research institutions, custom synthesis laboratories, and pharmaceutical manufacturers engaged in the development of new drug candidates.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug molecules, especially in oncology and central nervous system (CNS) therapeutic research.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Custom Synthesis & Contract Manufacturing: Used by CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target compounds on a commercial scale.
• API Development: Integral to the development and scale-up processes for new Active Pharmaceutical Ingredients, leveraging its pyrazolopyridine core.
• Biochemical Research: May be utilized as a reference standard or a tool compound in biochemical assays and pharmacological studies.

Basic Information

Item	Detail
Product Name	3-Cyclopropyl-6-Ethyl-1-(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid
CAS No.	1018053-62-7
Molecular Formula	C20H18FN3O2
Molecular Weight	351.38 g/mol
Synonyms	3-Cyclopropyl-6-ethyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1-(4-Fluorophenyl)-3-cyclopropyl-6-ethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1018053-62-7; 3-Cyclopropyl-6-ethyl-1-(4-fluorophenyl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; Pyrazolo[3,4-b]pyridine-4-carboxylic acid derivative
EINECS	Contact for details

Quality Control

Our 3-Cyclopropyl-6-Ethyl-1-(4-Fluorophenyl)Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.