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3,6-Dicyclopropyl-1-[2-(Ethylamino)-2-Oxoethyl]-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid CAS NO 1018052-15-7
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CAS No.:1018052-15-7
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
3,6-Dicyclopropyl-1-[2-(Ethylamino)-2-Oxoethyl]-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is critical for the research and development of novel therapeutic agents, particularly in the field of kinase inhibition. It is primarily sought by pharmaceutical R&D departments, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of targeted drug candidates.
Application
- Pharmaceutical Intermediate: Key building block in the synthesis of investigational new drugs (INDs), especially kinase inhibitors.
- Biochemical Research: Used as a reference standard or active compound in high-throughput screening (HTS) and target validation studies.
- Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
- Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP-scale production of active pharmaceutical ingredients (APIs).
- Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and drug discovery pathways.
Basic Information
| Product Name | 3,6-Dicyclopropyl-1-[2-(Ethylamino)-2-Oxoethyl]-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid |
| CAS No. | 1018052-15-7 |
| Molecular Formula | C19H22N4O3 |
| Molecular Weight | 354.41 g/mol |
| Synonyms | 3,6-Dicyclopropyl-1-[2-(ethylamino)-2-oxoethyl]-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid; 1H-Pyrazolo[3,4-b]pyridine-4-carboxylic acid, 3,6-dicyclopropyl-1-[2-(ethylamino)-2-oxoethyl]-; UNII-6V9Q2S2W1F; 6V9Q2S2W1F; CHEMBL3186665; ZINC000006245949; AKOS009158932; BDBM50389355 |
| EINECS | Contact for details |
Quality Control
Our 3,6-Dicyclopropyl-1-[2-(Ethylamino)-2-Oxoethyl]-1H-Pyrazolo[3,4-B]Pyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are provided with every shipment.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white powder |
| Identification (HPLC) | Conforms to reference standard |
| Identification (IR) | Conforms to structure |
| Assay (HPLC) | ≥ 98.0% |
| Water Content (KF) | ≤ 0.5% |
| Residue on Ignition | ≤ 0.1% |
| Heavy Metals | ≤ 10 ppm |
| Single Unknown Impurity (HPLC) | ≤ 0.5% |
| Total Impurities (HPLC) | ≤ 2.0% |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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