Description

1-(2,2-Difluoroethyl)-3-Methyl-4-(Trifluoromethyl)-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is a high-value, fluorinated heterocyclic compound that serves as a critical advanced intermediate in modern synthetic chemistry. Its unique structure, featuring multiple fluorine atoms, is engineered to impart desirable properties such as metabolic stability and enhanced lipophilicity in target molecules. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, particularly in oncology, CNS, and metabolic disease research.
• Agrochemical Research: Used in developing novel pesticides and herbicides where the fluorine atoms contribute to improved biological activity and environmental profile.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Investigated as a precursor for specialty polymers and advanced materials with unique electronic or surface properties.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and development programs.

Basic Information

Product Name	1-(2,2-Difluoroethyl)-3-Methyl-4-(Trifluoromethyl)-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One
CAS No.	1018051-29-0
Molecular Formula	C11H8F5N3O
Molecular Weight	293.20 g/mol
Synonyms	1-(2,2-Difluoroethyl)-3-methyl-4-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-6(7H)-one; 6H-Pyrazolo[3,4-b]pyridin-6-one, 1-(2,2-difluoroethyl)-1,7-dihydro-3-methyl-4-(trifluoromethyl)-; CAS 1018051-29-0; Fluorinated Pyrazolopyridinone Intermediate; DFMP Intermediate
EINECS	Contact for details

Quality Control

Every batch of 1-(2,2-Difluoroethyl)-3-Methyl-4-(Trifluoromethyl)-1,7-Dihydro-6H-Pyrazolo[3,4-B]Pyridin-6-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development applications. A detailed Certificate of Analysis (COA) including HPLC purity, NMR, and MS data is supplied with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is sensitive to fluoride and strong alkali. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.