Description

3-Phenyl-4-(trifluoromethyl)isoxazolo[5,4-b]pyridin-6(7H)-one is a high-value, heterocyclic organic compound featuring a fused isoxazole-pyridone core structure. This molecule is of significant interest in advanced pharmaceutical research and development, primarily due to its role as a sophisticated pharmaceutical intermediate or building block. It is specifically engineered for organizations engaged in the discovery and synthesis of novel active pharmaceutical ingredients (APIs), particularly within therapeutic areas requiring complex molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates, especially for small molecule therapeutics.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Agrochemical Development: Potential use as an intermediate in the research and synthesis of new generation crop protection agents and herbicides.
• Material Science Precursor: Can be utilized in the development of advanced organic electronic materials or specialty polymers.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects requiring high-purity, complex heterocycles.

Basic Information

Product Name	3-Phenyl-4-(trifluoromethyl)isoxazolo[5,4-b]pyridin-6(7H)-one
CAS No.	1018047-90-9
Molecular Formula	C14H7F3N2O2
Molecular Weight	292.22 g/mol
Synonyms	6H-Isoxazolo[5,4-b]pyridin-6-one, 3-phenyl-4-(trifluoromethyl)-; 3-Phenyl-4-(trifluoromethyl)-6H-isoxazolo[5,4-b]pyridin-6-one; 4-(Trifluoromethyl)-3-phenylisoxazolo[5,4-b]pyridin-6(7H)-one; 3-Phenyl-4-trifluoromethylisoxazolopyridinone; CAS 1018047-90-9; Isoxazolopyridinone derivative
EINECS	Contact for details

Quality Control

Our production of 3-Phenyl-4-(trifluoromethyl)isoxazolo[5,4-b]pyridin-6(7H)-one adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality systems are designed to support cGMP requirements for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.