Description

2-Boc-Amino-4,6-Dichloropyridine is a high-purity, protected amino pyridine derivative serving as a critical building block in advanced organic synthesis. Its primary value lies in providing a versatile and reactive scaffold for constructing complex heterocyclic molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and novel compound libraries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting central nervous system disorders, infectious diseases, and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the pyridine core's bioactivity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Peptidomimetic and PROTAC Research: The Boc-protected amine and dichloro-substituted pyridine structure is valuable for constructing peptide mimics and Proteolysis-Targeting Chimeras (PROTACs).
• Material Science Research: Employed in the synthesis of organic electronic materials, such as ligands for OLEDs and conductive polymers.
• Custom Synthesis and Contract Manufacturing: A fundamental building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.

Basic Information

Product Name	2-Boc-Amino-4,6-Dichloropyridine
CAS No.	1017789-38-6
Molecular Formula	C11H12Cl2N2O2
Molecular Weight	275.13 g/mol
Synonyms	tert-Butyl (4,6-dichloropyridin-2-yl)carbamate; 2-((tert-Butoxycarbonyl)amino)-4,6-dichloropyridine; 4,6-Dichloro-2-pyridinamine, N-BOC-; N-Boc-2-amino-4,6-dichloropyridine; 2-Amino-4,6-dichloropyridine N-Boc derivative; Boc-2-A-4,6-DCP; (4,6-Dichloro-2-pyridinyl)carbamic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 2-Boc-Amino-4,6-Dichloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP standards for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.