Description

Methyl 5-Bromo-2-Piperidinonicotinate CAS NO 1017783-01-5 is a high-purity, advanced pharmaceutical intermediate characterized by its brominated nicotinate core and piperidine substitution. This compound is of significant value in medicinal chemistry for its role as a versatile building block in the synthesis of complex bioactive molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly kinase inhibitors and other targeted small-molecule therapies.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Chemical Synthesis Building Block: Used in organic synthesis to introduce the 5-bromo-2-piperidinonicotinate moiety into more complex molecular architectures.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.

Basic Information

Product Name	Methyl 5-Bromo-2-Piperidinonicotinate
CAS No.	1017783-01-5
Molecular Formula	C12H15BrN2O2
Molecular Weight	299.17 g/mol
Synonyms	Methyl 5-bromo-2-(piperidin-1-yl)nicotinate; 5-Bromo-2-piperidin-1-yl-pyridine-3-carboxylic acid methyl ester; 2-Piperidino-5-bromonicotinic acid methyl ester; 3-Pyridinecarboxylic acid, 5-bromo-2-(1-piperidinyl)-, methyl ester; Methyl 5-bromo-2-(1-piperidinyl)nicotinate; 5-Bromo-2-(piperidin-1-yl)nicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Piperidinonicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request, supporting compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.