Description

Methyl 5-Bromo-2-Morpholinonicotinate is a high-purity, synthetically valuable heterocyclic building block. This compound is essential for medicinal chemistry research and the development of novel active pharmaceutical ingredients (APIs), particularly as a key intermediate in kinase inhibitor synthesis. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and advanced material scientists seeking to incorporate complex nicotinate motifs into their molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug candidates.
• Agrochemical Development: Serves as a building block for creating new crop protection agents with specific biological activity.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme function and cellular pathways.
• Organic Synthesis: A versatile reagent for constructing complex heterocyclic systems and functionalized pyridine derivatives.
• Material Science Research: Potential precursor for the development of organic electronic materials and ligands for catalytic systems.

Basic Information

Product Name	Methyl 5-Bromo-2-Morpholinonicotinate
CAS No.	1017782-99-8
Molecular Formula	C11H13BrN2O3
Molecular Weight	301.14 g/mol
Synonyms	5-Bromo-2-morpholin-4-ylpyridine-3-carboxylic acid methyl ester; Methyl 5-bromo-2-(morpholin-4-yl)nicotinate; 3-Pyridinecarboxylic acid, 5-bromo-2-(4-morpholinyl)-, methyl ester; 5-Bromo-2-morpholinonicotinic acid methyl ester; 1017782-99-8
EINECS	Contact for details

Quality Control

Our Methyl 5-Bromo-2-Morpholinonicotinate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research and development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.