Description

Ethyl 1-(n-(2-Bromoethyl)-n-(tert-Butoxycarbonyl)Sulfamoyl)Piperidine-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex sulfamoyl-piperidine scaffold. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially those targeting central nervous system (CNS) disorders and other specialized therapeutic pathways.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of complex drug molecules and investigational new drugs (INDs).
• Protease Inhibitor Research: Used in the development of inhibitors targeting specific enzymes, leveraging its sulfamoyl functional group.
• Chemical Biology & Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Peptidomimetic Synthesis: Acts as a constrained scaffold to mimic peptide structures in drug design, enhancing metabolic stability.
• CNS Drug Discovery: A valuable precursor in the research of therapeutics for neurological conditions due to its piperidine core.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom API synthesis projects under cGMP guidelines.

Basic Information

Product Name	Ethyl 1-(n-(2-Bromoethyl)-n-(tert-Butoxycarbonyl)Sulfamoyl)Piperidine-3-Carboxylate
CAS No.	1017782-89-6
Molecular Formula	C15H27BrN2O5S
Molecular Weight	427.36 g/mol
Synonyms	Ethyl 1-[(2-Bromoethyl)(tert-butoxycarbonyl)sulfamoyl]piperidine-3-carboxylate; 1-[(2-Bromoethyl)(tert-Butoxycarbonylamino)sulfonyl]piperidine-3-carboxylic Acid Ethyl Ester; 3-Carbethoxy-1-[(N-(2-bromoethyl)-N-(tert-butoxycarbonyl)sulfamoyl)]piperidine; BOC-Protected Sulfamoyl Piperidine Bromoethyl Ester; tert-Butyl N-(2-bromoethyl)-N-[(3-ethoxycarbonyl)piperidin-1-ylsulfonyl]carbamate
EINECS	Contact for details

Quality Control

Our production of Ethyl 1-(n-(2-Bromoethyl)-n-(tert-Butoxycarbonyl)Sulfamoyl)Piperidine-3-Carboxylate adheres to stringent quality protocols suitable for pharmaceutical R&D and pre-clinical development. Each batch is characterized and tested to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing comprehensive analytical results from techniques such as HPLC, NMR, and MS are provided with every shipment. We support development under quality systems aligned with ICH guidelines and can accommodate specific customer requirements for analytical methods and specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.