Description

2-[4-(2-Hydroxyethyl)Piperazino]Nicotinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a versatile piperazine-nicotinonitrile hybrid structure. This compound is valued for its role as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers for the creation of novel active pharmaceutical ingredients (APIs) and other bioactive compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a building block for creating complex heterocyclic compounds and specialty chemicals.
• Biochemical Research: Employed in the development of chemical probes and tool compounds for biological target validation.
• Contract Manufacturing (CMO): Supplied to contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	2-[4-(2-Hydroxyethyl)Piperazino]Nicotinonitrile
CAS No.	1017782-85-2
Molecular Formula	C12H16N4O
Molecular Weight	232.28 g/mol
Synonyms	2-(4-(2-Hydroxyethyl)piperazin-1-yl)nicotinonitrile; 2-[4-(2-Hydroxyethyl)-1-piperazinyl]-3-pyridinecarbonitrile; Nicotinonitrile, 2-[4-(2-hydroxyethyl)-1-piperazinyl]-; 3-Cyano-2-[4-(2-hydroxyethyl)piperazin-1-yl]pyridine
EINECS	Contact for details

Quality Control

Our 2-[4-(2-Hydroxyethyl)Piperazino]Nicotinonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D applications. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and other critical parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.