Description

Ethyl 1-(4-Amino-3-Methoxyphenyl)-4-Piperidinecarboxylate is a high-purity, advanced pharmaceutical intermediate of significant commercial and research interest. This compound serves as a critical building block in the synthesis of complex molecules, particularly in medicinal chemistry and drug discovery programs. It is essential for R&D and production teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking reliable, high-quality intermediates for API development.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and other therapeutic agents.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex piperidine-containing heterocycles and other pharmacophores.
• Contract Research & Manufacturing (CRAM): Supplied to CROs and CDMOs for custom synthesis projects and scale-up development.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Ethyl 1-(4-Amino-3-Methoxyphenyl)-4-Piperidinecarboxylate
CAS No.	1017782-48-7
Molecular Formula	C15H22N2O3
Molecular Weight	278.35 g/mol
Synonyms	Ethyl 4-(4-Amino-3-methoxyphenyl)piperidine-1-carboxylate; 1-Carbethoxy-4-(4-amino-3-methoxyphenyl)piperidine; 4-(4-Amino-3-methoxyphenyl)-1-piperidinecarboxylic acid ethyl ester; 1-Piperidinecarboxylic acid, 4-(4-amino-3-methoxyphenyl)-, ethyl ester; Ethyl 4-(4-Amino-3-methoxyphenyl)-1-piperidinecarboxylate; 4-(4-Amino-3-methoxyphenyl)piperidine-1-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-(4-Amino-3-Methoxyphenyl)-4-Piperidinecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Purity (HPLC, Area%)	≥99.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.