Description

[4-(2-p-Tolyl-Acetyl)-Benzyl]-Carbamic Acid tert-Butyl Ester is a sophisticated organic building block and key intermediate in advanced pharmaceutical synthesis. This compound matters for its role as a crucial precursor in the development of active pharmaceutical ingredients (APIs) and other high-value fine chemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in the research and development of protease inhibitors, targeting various therapeutic areas.
• Peptidomimetic Synthesis: Serves as a key component for constructing peptidomimetics, which are molecules that mimic peptides but with enhanced stability and bioavailability.
• Agrochemical Development: Employed as an intermediate in the synthesis of advanced crop protection agents and herbicides.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	[4-(2-p-Tolyl-Acetyl)-Benzyl]-Carbamic Acid tert-Butyl Ester
CAS No.	1017781-77-9
Molecular Formula	C21H25NO3
Molecular Weight	339.43 g/mol
Synonyms	tert-Butyl N-[[4-[2-(4-methylphenyl)-2-oxoethyl]phenyl]methyl]carbamate; Carbamic acid, N-[[4-[2-(4-methylphenyl)-2-oxoethyl]phenyl]methyl]-, 1,1-dimethylethyl ester; BOC-Protected [4-(2-p-Tolyl-Acetyl)-Benzyl]amine; 4-(2-(4-Methylbenzoyl)benzyl)carbamic acid tert-butyl ester; N-Boc-4-(2-(p-tolyl)-2-oxoethyl)benzylamine; (4-((tert-Butoxycarbonylamino)methyl)phenyl)(2-(p-tolyl)-2-oxoethyl) Ketone intermediate
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. We employ advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to verify identity, purity, and consistency. Certificates of Analysis (COA) are provided with each batch, detailing all critical quality attributes. Our quality management system supports cGMP compliance for advanced intermediates intended for pharmaceutical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.