Description

1'-Benzyl-6-Chloro-3H-Spiro[Furo[3,4-C]Pyridine-1,4'-Piperidin]-3-One is a high-purity, advanced pharmaceutical intermediate of significant interest in modern drug discovery. This compound matters due to its complex spirocyclic and fused heterocyclic architecture, which serves as a privileged scaffold for modulating biological targets. It is primarily needed by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates targeting G-protein-coupled receptors (GPCRs) and kinases.
• Medicinal Chemistry Research: Used in high-throughput screening (HTS) and structure-activity relationship (SAR) studies to explore new chemical entities.
• Preclinical Development: Serves as a critical precursor in the scale-up synthesis of lead compounds for toxicology and pharmacokinetic studies.
• Chemical Biology: Employed as a molecular probe to study enzyme inhibition and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for client projects.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1'-Benzyl-6-Chloro-3H-Spiro[Furo[3,4-C]Pyridine-1,4'-Piperidin]-3-One
CAS No.	1017598-71-8
Molecular Formula	C19H17ClN2O2
Molecular Weight	340.80 g/mol
Synonyms	1'-Benzyl-6-chloro-3H-spiro[furo[3,4-c]pyridine-1,4'-piperidin]-3-one; 6-Chloro-1'-benzyl-3H-spiro[furo[3,4-c]pyridine-1,4'-piperidin]-3-one; 1017598-71-8; Spiro[furo[3,4-c]pyridine-1,4'-piperidin]-3-one, 1'-benzyl-6-chloro-3H-; AKOS025147324; 1'-Benzyl-6-chloro-3H-spiro[furo[3,4-c]pyridine-1,4'-piperidine]-3-one; 1'-Benzyl-6-chloro-3H-spiro[furo[3,4-c]pyridine-1,4'-piperidin]-3-one
EINECS	Contact for details

Quality Control

Our 1'-Benzyl-6-Chloro-3H-Spiro[Furo[3,4-C]Pyridine-1,4'-Piperidin]-3-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.