Description

2,5-Dichloropyridine-4-Carbonyl Chloride is a high-purity, reactive heterocyclic building block essential for advanced organic synthesis. This compound serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for creating novel compounds with targeted biological activity.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in drug discovery for central nervous system (CNS) and anti-infective agents.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, leveraging the pyridine core for bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and metal complexation.
• Material Science Research: Employed in the synthesis of functionalized polymers and organic electronic materials due to its reactive acid chloride and halogenated pyridine structure.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke chemicals for clients.

Basic Information

Product Name	2,5-Dichloropyridine-4-Carbonyl Chloride
CAS No.	1017590-28-1
Molecular Formula	C7H2Cl3NO
Molecular Weight	230.45 g/mol
Synonyms	4-Pyridinecarbonyl chloride, 2,5-dichloro-; 2,5-Dichloroisonicotinoyl chloride; 2,5-Dichloro-4-pyridinecarbonyl chloride; 2,5-Dichloroisonicotinic acid chloride; Isonicotinoyl chloride, 2,5-dichloro-; 2,5-Dichloro-4-(chlorocarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our 2,5-Dichloropyridine-4-Carbonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.