Description

Ethyl 6-(4-Oxopiperidin-1-Yl)Nicotinate is a high-purity pharmaceutical intermediate and advanced building block. This compound is valued for its role as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor research. It is primarily needed by R&D chemists and process development teams in the pharmaceutical, biotechnology, and fine chemical industries for synthesizing complex molecules with potential therapeutic applications.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry Development: Serves as a key starting material (KSM) or advanced intermediate in scaling up API synthesis under cGMP conditions.
• Biochemical Research: Employed as a tool compound or precursor in biochemical assays and target validation studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research organizations for bespoke synthesis projects.

Basic Information

Product Name	Ethyl 6-(4-Oxopiperidin-1-Yl)Nicotinate
CAS No.	1016885-83-8
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	Ethyl 6-(4-oxopiperidin-1-yl)nicotinate; 1-(5-(Ethoxycarbonyl)pyridin-2-yl)piperidin-4-one; 6-(4-Oxo-1-piperidinyl)-3-pyridinecarboxylic acid ethyl ester; Ethyl 6-(4-oxo-1-piperidinyl)nicotinate; 3-Pyridinecarboxylic acid, 6-(4-oxo-1-piperidinyl)-, ethyl ester; Ethyl 6-(4-oxopiperidino)nicotinate
EINECS	Contact for details

Quality Control

Our Ethyl 6-(4-Oxopiperidin-1-Yl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.