Description

2-(4-Benzylpiperazin-1-yl)isonicotinonitrile is a high-purity, advanced pharmaceutical intermediate featuring a versatile piperazine-isonicotinonitrile core structure. This compound is critical for medicinal chemistry research and development, serving as a key building block in the synthesis of novel bioactive molecules. It is primarily utilized by R&D laboratories and pharmaceutical manufacturers focused on developing new therapeutic agents, particularly in the areas of central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting various receptors.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Employed in the research of compounds targeting neurological pathways, due to the piperazine moiety's prevalence in neuroactive molecules.
• Oncology Research: Serves as a building block for developing kinase inhibitors and other targeted cancer therapies.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic routes for clients.

Basic Information

Product Name	2-(4-Benzylpiperazin-1-yl)isonicotinonitrile
CAS No.	1016862-98-8
Molecular Formula	C17H17N5
Molecular Weight	291.35 g/mol
Synonyms	2-(4-Benzyl-1-piperazinyl)isonicotinonitrile; 2-(4-Benzylpiperazin-1-yl)pyridine-4-carbonitrile; 4-Cyano-2-(4-benzylpiperazin-1-yl)pyridine; 2-(4-Benzylpiperazin-1-yl)-4-cyanopyridine; 1016862-98-8; BPI (abbreviation); 2-(4-Bzl-piperazin-1-yl)isonicotinonitrile
EINECS	Contact for details

Quality Control

Every batch of 2-(4-Benzylpiperazin-1-yl)isonicotinonitrile is manufactured and tested under strict quality management systems. We guarantee high chemical purity and consistency, supported by comprehensive analytical documentation. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and impurity profiles as determined by advanced chromatographic and spectroscopic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC / MS)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.