Description

2-{3-Oxo-2H,3H-[1,2,4]Triazolo[4,3-A]Pyridin-2-Yl}Ethanethioamide is a high-purity, advanced pharmaceutical intermediate featuring a fused triazolopyridine core with a reactive ethanethioamide side chain. This compound is of significant commercial interest for its role as a critical building block in the synthesis of novel, biologically active molecules. It is primarily required by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Heterocyclic Compound Synthesis: The triazolopyridine scaffold is valuable for creating libraries of compounds for high-throughput screening.
• Agrochemical Development: Potential application as an intermediate in the research and synthesis of new crop protection agents.
• Material Science Research: Investigated for the development of specialty chemicals and functional materials due to its unique heterocyclic structure.

Basic Information

Product Name	2-{3-Oxo-2H,3H-[1,2,4]Triazolo[4,3-A]Pyridin-2-Yl}Ethanethioamide
CAS No.	1016852-31-5
Molecular Formula	C9H8N4OS
Molecular Weight	220.25 g/mol
Synonyms	2-(3-Oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-2-yl)ethanethioamide; 2-(3-Oxo-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-2-yl)ethanethioamide; Ethanethioamide, 2-(3-oxo-2H,3H-[1,2,4]triazolo[4,3-a]pyridin-2-yl)-; 1016852-31-5; [1,2,4]Triazolo[4,3-a]pyridine-2-ethanethioamide, 2,3-dihydro-3-oxo-; 2-(3-oxo-2,3-dihydro-[1,2,4]triazolo[4,3-a]pyridin-2-yl)ethanethioamide
EINECS	Contact for details

Quality Control

Our 2-{3-Oxo-2H,3H-[1,2,4]Triazolo[4,3-A]Pyridin-2-Yl}Ethanethioamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.