Description

2-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Ylsulfanyl)Propionic Acid is a high-value, multi-functional chemical intermediate designed for advanced synthesis. Its unique molecular structure, featuring a pyridine core with chloro and trifluoromethyl substituents linked via a thioether to a propionic acid group, makes it a critical building block for creating complex molecules with tailored properties. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries seeking to introduce specific bioactivity, metabolic stability, and lipophilicity into their target compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Serves as a vital building block for developing novel herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis, leveraging the pyridine and sulfur donor atoms.
• Material Science Research: Employed in the development of advanced organic materials, including liquid crystals and polymers with specific electronic properties.
• Custom Synthesis and Contract Manufacturing: A sought-after intermediate for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Ylsulfanyl)Propionic Acid
CAS No.	1016845-67-2
Molecular Formula	C9H5ClF3NO2S
Molecular Weight	283.65 g/mol
Synonyms	2-[(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio]propanoic acid; 2-((3-Chloro-5-(trifluoromethyl)pyridin-2-yl)thio)propionic acid; Propanoic acid, 2-[[3-chloro-5-(trifluoromethyl)-2-pyridinyl]thio]-; 1016845-67-2; 2-(3-Chloro-5-trifluoromethyl-pyridin-2-ylsulfanyl)-propionic acid
EINECS	Contact for details

Quality Control

Every batch of 2-(3-Chloro-5-(Trifluoromethyl)Pyridin-2-Ylsulfanyl)Propionic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency meet the exacting standards required for pharmaceutical and agrochemical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases, oxidizing agents, and sources of ignition. Due to its acidic nature, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.