Description

6-(4-Bromophenoxy)Nicotinonitrile is a specialized organic compound featuring a bromophenoxy-substituted pyridine core. This molecular structure makes it a valuable high-purity intermediate for advanced chemical synthesis, particularly in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the life sciences sector for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), especially for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its halogenated aromatic structure.
• Material Science: Serves as a precursor for functionalized ligands and monomers in the creation of advanced polymers and organic electronic materials.
• Chemical Biology: Employed as a probe or linker in bioconjugation chemistry and proteomics research due to its reactive nitrile group.
• Academic & Contract Research: Essential reagent for methodological development and novel synthetic route exploration in university and CRO laboratories.

Basic Information

Product Name	6-(4-Bromophenoxy)Nicotinonitrile
CAS No.	1016772-13-6
Molecular Formula	C12H7BrN2O
Molecular Weight	275.10 g/mol
Synonyms	6-(4-Bromophenoxy)-3-pyridinecarbonitrile; 3-Cyano-6-(4-bromophenoxy)pyridine; Nicotinonitrile, 6-(4-bromophenoxy)-; 6-(p-Bromophenoxy)nicotinonitrile; 2-Bromo-4-(5-cyanopyridin-2-yloxy)phenol (tautomer); 1016772-13-6; 6-(4-Bromophenoxy)pyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 6-(4-Bromophenoxy)Nicotinonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep the container sealed to protect this light-sensitive material from moisture and atmospheric contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.