Description

(2-Chloro-3-Pyridinyl)(4-Hydroxy-1-Piperidinyl)-Methanone is a high-purity, advanced pharmaceutical intermediate with a distinct molecular architecture combining pyridine and piperidine moieties. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers seeking to develop new therapeutic or agrochemical agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Used in the development of new pesticides or herbicides, leveraging its heterocyclic structure for biological activity.
• Medicinal Chemistry Building Block: Employed in structure-activity relationship (SAR) studies and lead optimization processes due to its modifiable chloro and hydroxy functional groups.
• Chemical Biology Probes: Serves as a scaffold for creating molecular probes to study enzyme function or protein-ligand interactions in biological systems.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	(2-Chloro-3-Pyridinyl)(4-Hydroxy-1-Piperidinyl)-Methanone
CAS No.	1016680-50-4
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	(2-Chloro-3-pyridinyl)(4-hydroxy-1-piperidinyl)methanone; (2-Chloro-3-pyridyl)(4-hydroxypiperidin-1-yl)methanone; 1-(2-Chloro-3-pyridinecarbonyl)-4-hydroxypiperidine; 4-Hydroxy-1-[(2-chloro-3-pyridinyl)carbonyl]piperidine; Methanone, (2-chloro-3-pyridinyl)(4-hydroxy-1-piperidinyl)-; 1016680-50-4; AKOS025244065
EINECS	Contact for details

Quality Control

Our (2-Chloro-3-Pyridinyl)(4-Hydroxy-1-Piperidinyl)-Methanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.