Description

Methyl (3R)-3-Amino-3-(Pyridin-3-Yl)Propanoate CAS NO 1016670-42-0 is a chiral, non-natural amino acid ester derivative featuring a pyridine moiety, serving as a critical building block in advanced organic synthesis. This compound is valued for its role as a key chiral intermediate in the development of active pharmaceutical ingredients (APIs) and other biologically active molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecular architectures with high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of chiral pesticides and herbicides where specific stereochemistry is crucial for bioactivity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Peptidomimetics Research: Incorporated into peptide analogs to enhance stability, bioavailability, and receptor binding affinity.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein interactions.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring high-purity chiral building blocks.

Basic Information

Product Name	Methyl (3R)-3-Amino-3-(Pyridin-3-Yl)Propanoate
CAS No.	1016670-42-0
Molecular Formula	C9H12N2O2
Molecular Weight	180.20 g/mol
Synonyms	(R)-Methyl 3-amino-3-(pyridin-3-yl)propanoate; (3R)-3-Amino-3-(3-pyridyl)propionic acid methyl ester; Methyl (R)-3-amino-3-(3-pyridyl)propionate; 3-Pyridinepropanoic acid, 3-amino-, methyl ester, (3R)-; (R)-3-Amino-3-(pyridin-3-yl)propanoic acid methyl ester; β-Amino-β-(3-pyridyl)propionic acid methyl ester, (R)-; Methyl (R)-3-amino-3-(pyridin-3-yl)propanoate
EINECS	Contact for details

Quality Control

Our production of Methyl (3R)-3-Amino-3-(Pyridin-3-Yl)Propanoate adheres to stringent quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure compliance with exacting customer specifications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment. We support development and commercial projects requiring standards consistent with cGMP and ICH guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.