Description

Ethyl 2-(4-Oxopiperidin-1-Yl)Nicotinate is a high-purity, advanced pharmaceutical intermediate characterized by its unique heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within the fields of oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) for drug discovery programs.
• Medicinal Chemistry Research: Used as a versatile scaffold for constructing compound libraries and exploring structure-activity relationships (SAR).
• Kinase Inhibitor Development: Serves as a core structural component in the research and production of potential kinase inhibitor candidates.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and reaction mechanisms.

Basic Information

Product Name	Ethyl 2-(4-Oxopiperidin-1-Yl)Nicotinate
CAS No.	1016524-78-9
Molecular Formula	C13H16N2O3
Molecular Weight	248.28 g/mol
Synonyms	Ethyl 2-(4-oxopiperidin-1-yl)nicotinate; 1-(2-Carbethoxy-3-pyridyl)-4-piperidone; 2-(4-Oxo-1-piperidinyl)-3-pyridinecarboxylic acid ethyl ester; Ethyl 2-(4-oxo-1-piperidinyl)nicotinate; 3-Pyridinecarboxylic acid, 2-(4-oxo-1-piperidinyl)-, ethyl ester; 1016524-78-9; 1-(2-Ethoxycarbonylpyridin-3-yl)piperidin-4-one
EINECS	Contact for details

Quality Control

Our Ethyl 2-(4-Oxopiperidin-1-Yl)Nicotinate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.