Description

Benzyl 2-(tert-Butyldimethylsilyloxy)Ethylcarbamate is a key protected intermediate in advanced organic synthesis, valued for its role in constructing complex molecular architectures. Its primary function is to safeguard reactive functional groups, such as amines and alcohols, during multi-step synthetic sequences, thereby enabling the production of high-value target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-purity building blocks for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing amino alcohol motifs.
• Peptide Synthesis: Used for the protection of amino groups during solid-phase and solution-phase peptide synthesis.
• Agrochemical Research: Serves as a key intermediate in the development of novel herbicides, fungicides, and insecticides.
• Academic & R&D Laboratories: Employed in medicinal chemistry and organic synthesis research for constructing complex natural products and novel chemical entities.
• Specialty Polymer Synthesis: Acts as a monomer or functionalizing agent in the production of specialized polymers with tailored properties.
• Bioconjugation Chemistry: Utilized in the preparation of linker molecules for attaching drugs, dyes, or other functionalities to biomolecules.

Basic Information

Product Name	Benzyl 2-(tert-Butyldimethylsilyloxy)Ethylcarbamate
CAS No.	1015856-26-4
Molecular Formula	C₁₆H₂₇NO₃Si
Molecular Weight	309.48 g/mol
Synonyms	Benzyl N-[2-[(tert-butyldimethylsilyl)oxy]ethyl]carbamate; Carbamic acid, N-[2-[(1,1-dimethylethyl)dimethylsilyl]oxy]ethyl]-, phenylmethyl ester; Bn-OSi(t-Bu)Me2-NH-CBz; 2-[(tert-Butyldimethylsilyl)oxy]ethylcarbamic Acid Benzyl Ester; Benzyl (2-((tert-butyldimethylsilyl)oxy)ethyl)carbamate; TBDMS-O-CH2-CH2-NH-CBz; N-Cbz-2-aminoethoxy-tert-butyldimethylsilane
EINECS	Contact for details

Quality Control

Our Benzyl 2-(tert-Butyldimethylsilyloxy)Ethylcarbamate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with cGMP and ICH guidelines for advanced intermediates used in pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.