Description

tert-Butyl 2-(Phenylmethylsulfonamido)Acetate is a high-purity synthetic intermediate of significant importance in modern organic synthesis. This compound serves as a crucial building block for the development of more complex molecules, particularly in pharmaceutical research and fine chemical manufacturing. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to construct novel sulfonamide-containing scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, especially those containing sulfonamide pharmacophores.
• Peptidomimetic Research: Used in the construction of peptide analogs and mimetics where the tert-butyl ester and sulfonamide groups provide protective and functional versatility.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides with enhanced properties.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for catalysis or metal-organic frameworks (MOFs).
• Custom Chemical Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects requiring protected glycine derivatives.
• Academic Research: A valuable reagent for methodological studies in organic chemistry, particularly in amide bond formation and protecting group strategies.

Basic Information

Product Name	tert-Butyl 2-(Phenylmethylsulfonamido)Acetate
CAS No.	1015856-04-8
Molecular Formula	C₁₄H₂₁NO₄S
Molecular Weight	299.39 g/mol
Synonyms	N-[(Benzylsulfonyl)glycine] tert-butyl ester; tert-Butyl N-(phenylmethylsulfonyl)glycinate; Glycine, N-[(phenylmethyl)sulfonyl]-, 1,1-dimethylethyl ester; 2-[(Benzylsulfonyl)amino]acetic acid tert-butyl ester; tert-Butyl (2-((phenylmethyl)sulfonamido)acetate); (tert-Butoxycarbonylmethyl)(phenylmethanesulfonyl)amine
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-(Phenylmethylsulfonamido)Acetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.