Description

5-Fluoro-4-Iodo-1H-Pyrrolo[2,3-B]Pyridine is a high-value, halogenated heterocyclic building block of significant interest in modern synthetic chemistry. Its core structure, featuring both fluorine and iodine substituents on a fused pyrrolopyridine scaffold, makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for use in medicinal chemistry, process development, and the discovery of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in kinase inhibitor programs and other small-molecule therapeutics.
• Medicinal Chemistry: Used for structure-activity relationship (SAR) studies and lead optimization due to its halogen handles for further functionalization via cross-coupling reactions.
• Agrochemical Research: Serves as a building block in the synthesis of new herbicides, fungicides, and insecticides, leveraging its unique halogenated heterocyclic core.
• Material Science Precursor: Potential use in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) or semiconductors, where its electron-deficient aromatic system is beneficial.
• Chemical Biology Probe Development: Utilized in the synthesis of molecular probes and tags for studying biological systems and target engagement.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Product Name	5-Fluoro-4-Iodo-1H-Pyrrolo[2,3-B]Pyridine
CAS No.	1015610-23-7
Molecular Formula	C7H4FIN2
Molecular Weight	277.02 g/mol
Synonyms	4-Iodo-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridine, 5-fluoro-4-iodo-; 5-Fluoro-4-iodo-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-iodo-7-azaindole; 4-Iodo-5-fluoro-7-azaindole; 5-F-4-I-7-AZA; 1015610-23-7 (CAS)
EINECS	Contact for details

Quality Control

Our 5-Fluoro-4-Iodo-1H-Pyrrolo[2,3-B]Pyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. For long-term storage, consider storage under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.