Description

tert-Butyl4-(1H-Pyrrolo[3,2-B]Pyridin-6-Yl)Piperazine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1015609-59-2. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the multi-step synthesis of active pharmaceutical ingredients (APIs) for clinical research and development.
• Kinase Inhibitor Development: A crucial scaffold for constructing candidate molecules targeting various kinase enzymes, which are implicated in cancer and inflammatory diseases.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization to improve drug potency, selectivity, and pharmacokinetic properties.
• Bioconjugation & Probe Synthesis: The piperazine and pyrrolopyridine motifs make it suitable for creating chemical probes and bioconjugates for biological target identification and validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting outsourced drug discovery and custom synthesis projects for global clients.

Basic Information

Product Name	tert-Butyl4-(1H-Pyrrolo[3,2-B]Pyridin-6-Yl)Piperazine-1-Carboxylate
CAS No.	1015609-59-2
Molecular Formula	C16H22N4O2
Molecular Weight	302.37 g/mol
Synonyms	1-Boc-4-(1H-pyrrolo[3,2-b]pyridin-6-yl)piperazine; 1-(tert-Butoxycarbonyl)-4-(1H-pyrrolo[3,2-b]pyridin-6-yl)piperazine; tert-Butyl 4-(1H-pyrrolo[3,2-b]pyridin-6-yl)piperazine-1-carboxylate; 6-(1-Boc-piperazin-4-yl)-1H-pyrrolo[3,2-b]pyridine; 1015609-59-2; BOC-Piperazine-Pyrrolopyridine Derivative
EINECS	Contact for details

Quality Control

Our production of tert-Butyl4-(1H-Pyrrolo[3,2-B]Pyridin-6-Yl)Piperazine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and reliability for sensitive R&D applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. Our manufacturing processes are designed to meet the exacting standards required for pharmaceutical development under a quality system aligned with ICH Q7 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.