Description

tert-Butyl3-Iodo-1H-Pyrrolo[2,3-B]Pyridin-5-Ylcarbamate CAS NO 1015609-19-4 is a high-value, halogenated pyrrolopyridine derivative, serving as a critical building block in modern pharmaceutical and agrochemical research. Its primary commercial value lies in its role as a versatile intermediate for constructing complex molecular architectures, particularly in the synthesis of kinase inhibitors and other targeted therapeutics. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require reliable, high-purity intermediates for advanced synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel kinase inhibitors and other small-molecule drug candidates targeting oncology, inflammation, and CNS disorders.
• Agrochemical Research: Used in the development of new active ingredients for crop protection, leveraging its heterocyclic core for bioactivity.
• Chemical Biology & Proteomics: Employed as a molecular probe or a tagged scaffold for studying protein-ligand interactions and enzyme function.
• Material Science: Potential building block for creating organic electronic materials and advanced polymers with specific optoelectronic properties.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations for custom synthesis and scale-up projects under cGMP or research-grade conditions.
• Academic Research: Utilized in university and institutional labs for methodological development in organic synthesis and medicinal chemistry.

Basic Information

Product Name	tert-Butyl3-Iodo-1H-Pyrrolo[2,3-B]Pyridin-5-Ylcarbamate
CAS No.	1015609-19-4
Molecular Formula	C12H14IN3O2
Molecular Weight	359.16 g/mol
Synonyms	tert-Butyl 3-iodo-1H-pyrrolo[2,3-b]pyridin-5-ylcarbamate; 5-[[(1,1-Dimethylethoxy)carbonyl]amino]-3-iodo-1H-pyrrolo[2,3-b]pyridine; 3-Iodo-5-((tert-butoxycarbonyl)amino)-1H-pyrrolo[2,3-b]pyridine; tert-Butyl (3-iodo-1H-pyrrolo[2,3-b]pyridin-5-yl)carbamate; 1H-Pyrrolo[2,3-b]pyridine-5-carboxamide, 3-iodo-N-(1,1-dimethylethoxy)-; BOC-3-Iodo-5-amino-7-azaindole; 3-Iodo-5-BOC-amino-7-azaindole; tert-Butyl 3-iodo-7-azaindol-5-ylcarbamate
EINECS	Contact for details

Quality Control

Our tert-Butyl3-Iodo-1H-Pyrrolo[2,3-B]Pyridin-5-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can align with research-grade or cGMP standards to meet the specific requirements of preclinical development and early-phase clinical manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Single Unknown Impurity (HPLC)	≤1.0%
Total Impurities (HPLC)	≤3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.