Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-2-Cyclopropyl- is a high-purity, advanced pharmaceutical intermediate belonging to the fused heterocyclic compound class. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic research. It is essential for medicinal chemists and process development scientists in pharmaceutical R&D and fine chemical manufacturing seeking to develop next-generation small molecule drugs.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of complex drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies for novel bioactive molecules.
• Process Chemistry Development: Employed in scaling up synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to organizations specializing in custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring new synthetic methodologies and biological mechanisms.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-2-Cyclopropyl-
CAS No.	1014613-52-5
Molecular Formula	C10H9ClN2
Molecular Weight	192.65 g/mol
Synonyms	4-Chloro-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine; 2-Cyclopropyl-4-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-2-cyclopropyl-7-azaindole; 2-Cyclopropyl-4-chloro-7-azaindole; 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-2-cyclopropyl-; 1014613-52-5; 4-Chloro-2-cyclopropyl-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-2-Cyclopropyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support customer needs for regulatory filings and process validation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere to ensure product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.