Description

1H-Pyrrolo[2,3-B]Pyridine-2-Methanol, 4-Bromo-1-(Phenylsulfonyl)- is a high-purity, advanced pharmaceutical intermediate with the CAS number 1014613-32-1. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel drug candidates. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of complex active pharmaceutical ingredients (APIs), particularly for kinase inhibitor programs.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for novel drug discovery.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of diverse chemical libraries for screening.
• Biochemical Tool Compound Development: Utilized in the research and development of probe molecules for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the life sciences industry.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Methanol, 4-Bromo-1-(Phenylsulfonyl)-
CAS No.	1014613-32-1
Molecular Formula	C14H11BrN2O3S
Molecular Weight	367.22 g/mol
Synonyms	4-Bromo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine-2-methanol; 4-Bromo-1-tosyl-1H-pyrrolo[2,3-b]pyridine-2-methanol (common misnomer); 1-(Phenylsulfonyl)-4-bromo-1H-pyrrolo[2,3-b]pyridine-2-methanol; 4-Bromo-1H-pyrrolo[2,3-b]pyridine-2-methanol, 1-(phenylsulfonyl)-; 1014613-32-1; 4-Bromo-1-(benzenesulfonyl)-1H-pyrrolo[2,3-b]pyridin-2-ylmethanol
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Methanol, 4-Bromo-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.