Description

tert-Butyl 6,7-Dimethyl-4- Oxo-3,4-Dihydro-1η-Spiro[Chromene-2,4'-Piperidine]-1'-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex spirocyclic structure. This compound is of significant value for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and complex organic syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of proprietary drug candidates and novel APIs.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Organic Synthesis Building Block: Employed in constructing complex spirocyclic and heterocyclic frameworks for specialized chemical libraries.
• Contract Research & Development (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	tert-Butyl 6,7-Dimethyl-4- Oxo-3,4-Dihydro-1η-Spiro[Chromene-2,4'-Piperidine]-1'-Carboxylate
CAS No.	1013333-61-3
Molecular Formula	C20H27NO4
Molecular Weight	345.44 g/mol
Synonyms	1'-Boc-6,7-dimethyl-4-oxo-1,4-dihydrospiro[chromene-2,4'-piperidine]; tert-Butyl 6,7-dimethyl-4-oxo-1,4-dihydrospiro[chromene-2,4'-piperidine]-1'-carboxylate; 1,4-Dihydrospiro[chromene-2,4'-piperidine]-1'-carboxylic acid, 6,7-dimethyl-4-oxo-, 1,1-dimethylethyl ester; 6,7-Dimethyl-4-oxo-3,4-dihydro-1H-spiro[chromene-2,4'-piperidine]-1'-carboxylic acid tert-butyl ester; Spiro[chromene-2,4'-piperidine] intermediate; Boc-protected spirochromene piperidine.
EINECS	Contact for details

Quality Control

Our tert-Butyl 6,7-Dimethyl-4- Oxo-3,4-Dihydro-1η-Spiro[Chromene-2,4'-Piperidine]-1'-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided to support your R&D and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed under an inert atmosphere to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.