Description

Ethanone, 1-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1011711-52-6. This compound is a critical building block in modern medicinal chemistry, valued for its role in constructing complex heterocyclic scaffolds. It is primarily sought after by research institutions and pharmaceutical manufacturers engaged in the development of novel small-molecule therapeutics, particularly kinase inhibitors and other targeted agents.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of active pharmaceutical ingredients (APIs), especially for oncology and antiviral drug candidates.
• Kinase Inhibitor Development: Serves as a core structural motif in the design and synthesis of potent and selective kinase inhibitors, a major class of targeted cancer therapies.
• Medicinal Chemistry Research: Used extensively in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities with therapeutic potential.
• Biochemical Tool Compound: Employed in biochemical assays and as a reference standard for pharmacological and metabolic studies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting drug discovery and development pipelines for global clients.

Basic Information

Product Name	Ethanone, 1-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)-
CAS No.	1011711-52-6
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	1-(4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl)ethanone; 4-Chloro-3-acetyl-1H-pyrrolo[2,3-b]pyridine; 3-Acetyl-4-chloro-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-1H-pyrrolo[2,3-b]pyridin-3-yl methyl ketone; 1011711-52-6; 4-Chloro-3-acetyl-7-azaindole
EINECS	Contact for details

Quality Control

Our Ethanone, 1-(4-Chloro-1H-Pyrrolo[2,3-B]Pyridin-3-Yl)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep the container sealed to protect this light-sensitive material from degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.