Description

2-{[(6-Chloro-7-Hydroxy-2-Oxo-2H-Chromen-4-Yl)Methyl]Sulfanyl}-4,6-Dimethylpyridine-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate and research chemical of significant synthetic interest. This compound matters for its role as a key building block in the development of novel active pharmaceutical ingredients (APIs), particularly those targeting specific enzymatic pathways. Industrial and academic researchers in pharmaceutical R&D, agrochemical synthesis, and fine chemical manufacturing require this material for its unique molecular scaffold.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially in oncology and anti-inflammatory research.
• Chemical Biology Probe: Used in research to study enzyme inhibition and protein-ligand interactions due to its coumarin-pyridine hybrid structure.
• Agrochemical Research: Serves as a starting material for developing new crop protection agents with potential herbicidal or fungicidal activity.
• Organic Synthesis Building Block: Utilized in complex multi-step syntheses to introduce specific functional groups and heterocyclic systems.
• Material Science Research: Investigated for potential applications in creating novel organic electronic materials or fluorescent markers.

Basic Information

Product Name	2-{[(6-Chloro-7-Hydroxy-2-Oxo-2H-Chromen-4-Yl)Methyl]Sulfanyl}-4,6-Dimethylpyridine-3-Carbonitrile
CAS No.	1011625-29-8
Molecular Formula	C₁₈H₁₃ClN₂O₃S
Molecular Weight	372.82 g/mol
Synonyms	4-[(3-Cyano-4,6-dimethyl-2-pyridinyl)thio]methyl-6-chloro-7-hydroxy-2H-1-benzopyran-2-one; 2-(((6-Chloro-7-hydroxy-2-oxo-2H-chromen-4-yl)methyl)thio)-4,6-dimethylnicotinonitrile; 6-Chloro-7-hydroxy-4-(((3-cyano-4,6-dimethylpyridin-2-yl)thio)methyl)coumarin; 2-[(6-Chloro-7-hydroxy-2-oxochromen-4-yl)methylsulfanyl]-4,6-dimethylpyridine-3-carbonitrile; CAS 1011625-29-8
EINECS	Contact for details

Quality Control

Our 2-{[(6-Chloro-7-Hydroxy-2-Oxo-2H-Chromen-4-Yl)Methyl]Sulfanyl}-4,6-Dimethylpyridine-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D and fine chemical synthesis. Certificates of Analysis (COA) with detailed HPLC, NMR, and MS data are provided to guarantee traceability and batch-to-batch reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.